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KMID : 0964020090090010045
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Journal of the Korean Liver Cancer Study Group
2009 Volume.9 No. 1 p.45 ~ p.48
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Rapid recurrence following Living donor Liver transplantation for hepatocellular carcinoma within Milan criteria
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Woo Hyun-Young
Kwon Jung-Hyun
Kim Dong-Goo
You Young-Kyoung
Bae Si-Hyun
Rha Sung-Eun
Byun Jae-Young
Yoon Seung-Kew
Choi Byung-Gil
Kim Jin-Dong
Choi Jong-Young
Lee Hae-Giu
Chun Ho-Jong
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Abstract
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Liver transplantation is curative therapy for hepatocellular carcinoma especially if ,within Milan criteria, 4 year survival
and recurrence-free survival was reported to be 85% and 92%, respectively. Herein we report a patient who experience rapid recurrence following living donor liver transplantation (LDLT) for hepatocellular carcinoma within Milan criteria. A 52 year-old-men patient with known liver cirrhosis associated with hepatitis B virus was admitted for the treatment of
hepatocellular carcinoma (HCC). Abdominal CT revealed two nodules less than 3 cm in right hepatic lobe. After single
session of transcatheter arterial chemoembolization (TACE), the patient underwent LDLT. After seven months following
transplantation, recurrent HCC was detected on transplanted liver with concurrent metastatic nodule in lung. Although TACE and metastsectomy were performed for recurrent intrahepatic mass and lung metastasis, recurrent HCC showed rapid progression and patient died of progressive tumor after 10 months following LDLT.
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KEYWORD
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Hepatocellular carcinoma, Recurrence, Liver transplantation, Milan criteria
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